Article
Evaluation of new GenoType MTBDRplus for detection of resistance in cultures and direct specimens of Mycobacterium tuberculosis.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease - 1 Dec 2008
Causse M, Ruiz P, Gutierrez J B, Zerolo J, Casal M
Abstract excerpt
SETTINGS: Molecular methods frequently used in laboratories can now give us useful information about low growth bacteria. OBJECTIVE: To evaluate the new GenoType MTBDRplus assay for its ability to detect mutations in the 81-bp hotspot region of the rpoB gene, mutations in codon 315 of the katG gene and alterations in the inhA promoter region. DESIGN: Prospective resistance to rifampicin (RMP) and isoniazid (INH)...
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