Article
Dopamine D2 receptor Taq IA polymorphism is associated with postoperative nausea and vomiting.
Journal of anesthesia - 1 Jan 2008
Nakagawa Masashi, Kuri Michioki, Kambara Noriko, Tanigami Hironobu, Tanaka Hideo, Kishi Yoshihiko, Hamajima Nobuyuki
Abstract excerpt
PURPOSE: The dopamine D2 receptor (DRD2) is considered to be involved in the development of postoperative nausea and vomiting (PONV). Our aim was to examine the relationship between DRD2 Taq IA polymorphism and the occurrence of PONV. METHODS: We enrolled 1070 patients who were scheduled to undergo elective surgery under general anesthesia. Patients who vomited or required rescue antiemetics for severe nausea at...
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