Article
Relapse-free survival in breast cancer patients is associated with a gene expression signature characteristic for inflammatory breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Nov 2008
Van Laere Steven, Beissbarth Tim, Van der Auwera Ilse, Van den Eynden Gert, Trinh Xuan Bich, Elst Hilde, Van Hummelen Paul, van Dam Peter, Van Marck Eric, Vermeulen Peter, Dirix Luc
Abstract excerpt
PURPOSE: We hypothesize that a gene expression profile characteristic for inflammatory breast cancer (IBC), an aggressive form of breast cancer associated with rapid cancer dissemination and poor survival, might be related to tumor aggressiveness in non-IBC (nIBC). EXPERIMENTAL DESIGN: RNA from 17 IBC samples and 40 nIBC samples was hybridized onto Affymetrix chips. A gene signature predictive of IBC was...
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