Article
Molecular heterogeneity of inflammatory breast cancer: a hyperproliferative phenotype.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Sept 2006
Nguyen Dang M, Sam Kathy, Tsimelzon Anna, Li Xiaoxian, Wong Helen, Mohsin Syed, Clark Gary M, Hilsenbeck Susan G, Elledge Richard M, Allred D Craig, O'Connell Peter, Chang Jenny C
Abstract excerpt
PURPOSE: Inflammatory breast cancer (IBC) is associated with very poor prognosis. The aims of this study are (a) to prospectively identify differential gene expression patterns associated with IBC and (b) to confirm these pathways using tissue arrays. EXPERIMENTAL DESIGN: For gene expression analysis, IBC (n=14) was clinically defined as rapid-onset cancer associated with erythema and skin changes, whereas...
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