Article
E6 variants of human papillomavirus 18 differentially modulate the protein kinase B/phosphatidylinositol 3-kinase (akt/PI3K) signaling pathway.
Virology - 5 Jan 2009
Contreras-Paredes Adriana, De la Cruz-Hernández Erick, Martínez-Ramírez Imelda, Dueñas-González Alfonso, Lizano Marcela
Abstract excerpt
Intra-type genome variations of high risk Human papillomavirus (HPV) have been associated with a differential threat for cervical cancer development. In this work, the effect of HPV18 E6 isolates in Akt/PKB and Mitogen-associated protein kinase (MAPKs) signaling pathways and its implication in ce...
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