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Article

A novel hereditary spastic paraplegia with dystonia linked to chromosome 2q24-2q31.

Movement disorders : official journal of the Movement Disorder Society - 15 Feb 2009

Gilbert Donald L, Leslie Elizabeth J, Keddache Mehdi, Leslie Nancy D

Abstract excerpt

Spastic paraplegias (HSPs) and dystonias (DYTs) typically localize to different neuroanatomic systems. We report clinical and genetic data from large Ohio kindred with autosomal dominant (AD) HSP and DYT. Single and multipoint linkage using microsatellite and single nucleotide polymorphism array genotyping were performed on a large, multigenerational family with a novel, AD, highly penetrant neurological disease...

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Share to Chromosomes, Human, Pair 2
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19006192
DOI: 10.1002/mds.22363

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