Article
Bone inflammation and altered gene expression with type I diabetes early onset.
Journal of cellular physiology - 1 Mar 2009
Motyl Katherine J, Botolin Sergiu, Irwin Regina, Appledorn Daniel M, Kadakia Tejas, Amalfitano Andrea, Schwartz Richard C, McCabe Laura R
Abstract excerpt
Type I diabetes is associated with bone loss and marrow adiposity. To identify early events involved in the etiology of diabetic bone loss, diabetes was induced in mice by multiple low dose streptozotocin injections. Serum markers of bone metabolism and inflammation as well as tibial gene express...
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