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Article

Genome-wide screen of Saccharomyces cerevisiae null allele strains identifies genes involved in selenomethionine resistance.

Proceedings of the National Academy of Sciences of the United States of America - 18 Nov 2008

Bockhorn Jessica, Balar Bharvi, He Dongming, Seitomer Eden, Copeland Paul R, Kinzy Terri Goss

Abstract excerpt

Selenomethionine (SeMet) is a potentially toxic amino acid, and yet it is a valuable tool in the preparation of labeled proteins for multiwavelength anomalous dispersion or single-wavelength anomalous dispersion phasing in X-ray crystallography. The mechanism by which high levels of SeMet exhibits its toxic effects in eukaryotic cells is not fully understood. Attempts to use Saccharomyces cerevisiae for the...

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Identifiers

PMID: 19004804
DOI: 10.1073/pnas.0805642105
PMCID: PMC2584752

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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