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Article

Altered functional properties of a TRPM2 variant in Guamanian ALS and PD.

Proceedings of the National Academy of Sciences of the United States of America - 18 Nov 2008

Hermosura Meredith C, Cui Aaron M, Go Ramon Christopher V, Davenport Bennett, Shetler Cory M, Heizer Justin W, Schmitz Carsten, Mocz Gabor, Garruto Ralph M, Perraud Anne-Laure

Abstract excerpt

Two related neurodegenerative disorders, Western Pacific amyotrophic lateral sclerosis (ALS) and parkinsonism-dementia (PD), originally occurred at a high incidence on Guam, in the Kii peninsula of Japan, and in southern West New Guinea more than 50 years ago. These three foci shared a unique min...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19004782
DOI: 10.1073/pnas.0808218105
PMCID: PMC2584682

Genes

TRPM2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19004782-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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