Mapping of the gene for a major penicillin-binding protein to a genetically conserved region of the Bacillus subtilis chromosome and conservation of the protein among related species of Bacillus.

Abstract excerpt

Penicillin-binding protein 5 is the most abundant penicillin-binding protein in the vegetative membranes of Bacillus subtilis and accounts for 95% of the D,D-carboxypeptidase activity of the cell. The structural gene for penicillin-binding protein 5 was mapped to a genetically conserved region near guaB at 0 degrees on the B. subtilis chromosome, and immunoassays revealed that there is conservation of this major...

Topics

• Bacillus
• Bacillus subtilis
• Bacterial Proteins
• Carrier Proteins
• Chromosome Mapping
• Chromosomes, Bacterial
• Genes, Bacterial
• Hexosyltransferases
• Muramoylpentapeptide Carboxypeptidase
• Penicillin-Binding Proteins