Article
Two class A high-molecular-weight penicillin-binding proteins of Bacillus subtilis play redundant roles in sporulation.
Journal of bacteriology - 1 Oct 2001
McPherson D C, Driks A, Popham D L
Abstract excerpt
The four class A penicillin-binding proteins (PBPs) of Bacillus subtilis appear to play functionally redundant roles in polymerizing the peptidoglycan (PG) strands of the vegetative-cell and spore walls. The ywhE product was shown to bind penicillin, so the gene and gene product were renamed pbpG and PBP2d, respectively. Construction of mutant strains lacking multiple class A PBPs revealed that, while PBP2d plays...
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