Article
A yeast protein with homology to the beta-subunit of G proteins is involved in control of heme-regulated and catabolite-repressed genes.
Gene - 15 Jan 1991
Zhang M, Rosenblum-Vos L S, Lowry C V, Boakye K A, Zitomer R S
Abstract excerpt
The product of the Saccharomyces cerevisiae AER2 gene is responsible for maintaining repression of at least two distinct regulatory pathways: heme activation/repression and catabolite repression. Mutations in the gene caused an eightfold increase in the expression of the heme-activated CYC1 gene in the absence of heme, a substantial increase in the expression of the heme-repressed ANB1 gene in the presence of...
Topics
- Amino Acid Sequence
- Base Sequence
- Chromosome Mapping
- Chromosomes, Fungal
- Cloning, Molecular
- Fungal Proteins
- GTP-Binding Proteins
- Gene Expression Regulation, Fungal
- Genes, Fungal
- Genes, Regulator