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Article

Synergistic repression of anaerobic genes by Mot3 and Rox1 in Saccharomyces cerevisiae.

Nucleic acids research - 15 Oct 2003

Sertil Odeniel, Kapoor Rachna, Cohen Brian D, Abramova Natalia, Lowry Charles V

Abstract excerpt

Two groups of anaerobic genes (genes induced in anaerobic cells and repressed in aerobic cells) are negatively regulated by heme, a metabolite present only in aerobic cells. Members of both groups, the hypoxic genes and the DAN/TIR/ERG genes, are jointly repressed under aerobic conditions by two factors. One is Rox1, an HMG protein, and the second, originally designated Rox7, is shown here to be Mot3, a global...

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Identifiers

PMID: 14530431
DOI: 10.1093/nar/gkg792
PMCID: PMC219473

Genes

ERG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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