Article
Age-related bone loss in the LOU/c rat model of healthy ageing.
Experimental gerontology - 1 Mar 2009
Duque Gustavo, Rivas Daniel, Li Wei, Li Ailian, Henderson Janet E, Ferland Guylaine, Gaudreau Pierrette
Abstract excerpt
Inbred albino Louvain (LOU) rats are considered a model of healthy aging due to their increased longevity in the absence of obesity and with a low incidence of common age-related diseases. In this study, we characterized the bone phenotype of male and female LOU rats at 4, 20 and 27 months of age using quantitative micro computed tomographic (mCT) imaging, histology and biochemical analysis of circulating bone...
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