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Article

An unbiased estimator of gene diversity in samples containing related individuals.

Molecular biology and evolution - 1 Mar 2009

DeGiorgio Michael, Rosenberg Noah A

Abstract excerpt

Gene diversity is sometimes estimated from samples that contain inbred or related individuals. If inbred or related individuals are included in a sample, then the standard estimator for gene diversity produces a downward bias caused by an inflation of the variance of estimated allele frequencies. We develop an unbiased estimator for gene diversity that relies on kinship coefficients for pairs of individuals with...

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Identifiers

PMID: 18988687
DOI: 10.1093/molbev/msn254
PMCID: PMC2915906

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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