Article
Support from the relationship of genetic and geographic distance in human populations for a serial founder effect originating in Africa.
Proceedings of the National Academy of Sciences of the United States of America - 1 Nov 2005
Ramachandran Sohini, Deshpande Omkar, Roseman Charles C, Rosenberg Noah A, Feldman Marcus W, Cavalli-Sforza L Luca
Abstract excerpt
Equilibrium models of isolation by distance predict an increase in genetic differentiation with geographic distance. Here we find a linear relationship between genetic and geographic distance in a worldwide sample of human populations, with major deviations from the fitted line explicable by admixture or extreme isolation. A close relationship is shown to exist between the correlation of geographic distance and...
Topics
- Africa
- Founder Effect
- Genetic Drift
- Genetic Heterogeneity
- Genetic Variation
- Genetics, Population
- Geography
- Humans
- Models, Genetic
- Selection, Genetic