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Article

Distinctive localization of antigen-presenting cells in human lymph nodes.

Blood - 5 Feb 2009

Angel Catherine E, Chen Chun-Jen J, Horlacher Oliver C, Winkler Sintia, John Thomas, Browning Judy, MacGregor Duncan, Cebon Jonathan, Dunbar P Rod

Abstract excerpt

Professional antigen-presenting cells (APCs) are sentinel cells of the immune system that present antigen to T lymphocytes and mediate an appropriate immune response. It is therefore surprising that knowledge of the professional APCs in human lymph nodes is limited. Using 3-color immunohistochemistry, we have identified APCs in human lymph nodes, excluding plasmacytoid APCs, that fall into 2 nonoverlapping...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18987360
DOI: 10.1182/blood-2008-06-165266
PMCID: PMC2687552

Genes

APC

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