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Article

Long-term effects of inducible mutagenic DNA repair on relative fitness and phenotypic diversification in Pseudomonas cichorii 302959.

Genetics - 1 Jan 2009

Weigand Michael R, Sundin George W

Abstract excerpt

Mutagenic DNA repair (MDR) employs low-fidelity DNA polymerases capable of replicating past DNA lesions resulting from exposure to high-energy ultraviolet radiation (UVR). MDR confers UVR tolerance and activation initiates a transient mutator phenotype that may provide opportunities for adaptation. To investigate the potential role of MDR in adaptation, we have propagated parallel lineages of the highly mutable...

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Source

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Identifiers

PMID: 18984570
DOI: 10.1534/genetics.108.096131
PMCID: PMC2621168

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Source receipt: pubmed, retrieved 7 Sept 2026.

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