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A Unifying Nitrososynthase Involved in Nitrosugar Biosynthesis

5 Nov 2008

Abstract excerpt

Herein we describe the cloning, functional expression and initial characterization of ORF36 from Micromonospora carbonacae var. africana and rubN8 from Streptomyces achromogenes var. rubradiris. The purified enzymes play the same role, the double-oxidation of TDP-evernosamine to TDP-evernitrosose in the everninomycin and rubradirin pathways, respectively.

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PMID: 18983146
DOI: 10.1021/ja8051415

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