Article
The genetic variation in the tenomodulin gene is associated with serum total and LDL cholesterol in a body size-dependent manner.
International journal of obesity (2005) - 1 Dec 2008
Tolppanen A-M, Pulkkinen L, Kuulasmaa T, Kolehmainen M, Schwab U, Lindström J, Tuomilehto J, Uusitupa M, Kuusisto J
Abstract excerpt
We have reported that the sequence variation in the tenomodulin (TNMD) gene is associated with the risk of type 2 diabetes (T2DM), central obesity and serum levels of systemic immune mediators in the Finnish Diabetes Prevention Study (DPS), which is a longitudinal lifestyle intervention study on 522 middle-aged persons with impaired glucose tolerance (IGT). The aim of this study was to investigate whether the...
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