Article
Independent risk factors and predictive score for the development of hepatocellular carcinoma in chronic hepatitis B.
Journal of hepatology - 1 Jan 2009
Yuen Man-Fung, Tanaka Yasuhito, Fong Daniel Yee-Tak, Fung James, Wong Danny Ka-Ho, Yuen John Chi-Hang, But David Yiu-Kuen, Chan Annie On-On, Wong Benjamin Chun-Yu, Mizokami Masashi, Lai Ching-Lung
Abstract excerpt
BACKGROUND/AIMS: To determine whether gender, age, hepatitis B virus genotype, core promoter and precore mutations, HBeAg/ anti-HBe status, HBV DNA, ALT levels and cirrhosis on presentation were independent risk factors and derive a novel risk score for the development of HCC. METHODS: CHB patients (820) were followed up (mean duration 76.8 months) for the occurrence of HCC. RESULTS: The 5- and 10-year prevalence...
Topics
- Adolescent
- Adult
- Age Factors
- Aged
- Aged, 80 and over
- Carcinoma, Hepatocellular
- DNA, Viral
- Female
- Genotype
- Hepatitis B virus