Article
Characteristics and outcome of BRCA mutated epithelial ovarian cancer patients in Italy: A retrospective multicenter study (MITO 21).
Gynecologic oncology - 1 Jun 2021
Artioli Grazia, Giannone Gaia, Valabrega Giorgio, Maggiorotto Furio, Genta Sofia, Pignata Sandro, Lorusso Domenica, Cormio Gennaro, Scalone Simona, Nicoletto Maria Ornella, Greco Filippo, Rossi Emanuela, Spagnoletti Ilaria, De Giorgi Ugo, Orditura Michele, Mosconi Anna Maria, Kardhashi Anila, Bogliolo Stefano, Borgato Lucia
Abstract excerpt
OBJECTIVE: Around 15% of epithelial ovarian cancer (EOC) patients (pts) harbor a germline BRCA1 or 2 mutation, showing different features than BRCA wild-type pts. The clinical and pathological features of an Italian BRCA mutated EOC cohort were described. METHODS: We retrospectively analyzed clinical, pathological and mutational data from a cohort of Italian BRCA mutated EOC pts. treated in 15 MITO centers...
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