Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Role of CLCA Proteins in Inflammatory Airway Disease

27 Oct 2008

Abstract excerpt

Inflammatory airway diseases such as asthma and chronic obstructive pulmonary disease (COPD) exhibit stereotyped traits that are variably expressed in each person. In experimental mouse models of chronic lung disease, these individual disease traits can be genetically segregated and thereby linked to distinct determinants. Functional genomic analysis indicates that at least one of these traits, mucous cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asthma and respiratory diseases
Share to Ion channel regulation and function
Share to Ion Channels and Receptors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18954282
DOI: 10.1146/annurev.physiol.010908.163253

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Role of CLCA Proteins in Inflammatory Airway DiseasePMID 18954282Read ↗

Genetic segregation of airway disease traits despite redundancy of calcium-activated chloride channel family membersSemantic proximity Read ↗

Mucus as a Treatable Trait in Chronic Airway Diseases.Semantic proximity Read ↗

Chloride channels regulate differentiation and barrier functions of the mammalian airwaySemantic proximity Read ↗

Cox4i2, Ifit2, and Prdm11 Mutant Mice: Effective Selection of Genes Predisposing to an Altered Airway Inflammatory Response from a Large Compendium of Mutant Mouse Lines.Semantic proximity Read ↗

Chloride channel accessory 1 gene deficiency causes selective loss of mucus production in a new pig modelSemantic proximity Read ↗

Single Cell RNAseq Reveals A Critical Role of Chloride Channels in Airway DevelopmentSemantic proximity Read ↗

KCa3.1 differentially regulates trachea and bronchi epithelial gene expression in a chronic-asthma mouse modelSemantic proximity Read ↗

Transmembrane protein 16A (TMEM16A) is a Ca2+-regulated Cl- secretory channel in mouse airways.Semantic proximity Read ↗

MUC5B Idiopathic Pulmonary Fibrosis Risk Variant Promotes a Mucosecretory Phenotype and Loss of Small Airway Secretory CellsSemantic proximity Read ↗

ClC chloride channels in epithelia: recent progress and remaining puzzles.Semantic proximity Read ↗

Ion Channels in AsthmaSemantic proximity Read ↗

Regulation of Mucin Genes in Chronic Inflammatory Airway DiseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.