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Article

Predictive diagnosis of myotonic dystrophy with flanking microsatellite markers.

Journal of medical genetics - 1 Jul 1991

Mulley J C, Gedeon A K, White S J, Haan E A, Richards R I

Abstract excerpt

Linkage was shown between the myotonic dystrophy locus (DM) and a highly polymorphic AC repeat marker within the kallikrein (KLK1) locus (Z = 3.00, theta = 0.0). Linkage between KLK1 and the highly polymorphic AC repeat marker within the apolipoprotein C2 (APOC2) locus, which had been established in normal families, was confirmed in myotonic dystrophy families (Z = 4.37, theta = 0.11). These highly polymorphic AC...

Topics

Base Sequence
Female
Genetic Linkage
Genetic Markers
Genotype
Humans
Male
Molecular Sequence Data
Myotonic Dystrophy
Pedigree
Polymerase Chain Reaction
Predictive Value of Tests

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Prevalence

Recombination, Genetic

Risk

Source

Open in PubMed Open full text

Identifiers

PMID: 1895314
DOI: 10.1136/jmg.28.7.448
PMCID: PMC1016953

Genes

KLK1
APOC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1895314-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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