Article
Detection of linkage disequilibrium between the myotonic dystrophy locus and a new polymorphic DNA marker.
American journal of human genetics - 1 Jul 1991
Harley H G, Brook J D, Floyd J, Rundle S A, Crow S, Walsh K V, Thibault M C, Harper P S, Shaw D J
Abstract excerpt
We have examined the linkage of two new polymorphic DNA markers (D19S62 and D19S63) and a previously unreported polymorphism with an existing DNA marker (ERCC1) to the myotonic dystrophy (DM) locus. In addition, we have used pulsed-field gel electrophoresis to obtain a fine-structure map of this region. The detection of linkage disequilibrium between DM and one of these markers (D19S63) is the first demonstration...
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