Five years experience of predictive testing for myotonic dystrophy using linked DNA markers.

doi:10.1002/ajmg.1320430618

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Article

Five years experience of predictive testing for myotonic dystrophy using linked DNA markers.

American journal of medical genetics - 1 Aug 1992

Reardon W, Floyd J L, Myring J, Lazarou L P, Meredith A L, Harper P S

Abstract excerpt

We report on a 5 year experience in providing presymptomatic and prenatal molecular diagnostic services for myotonic dystrophy, using closely linked markers, representing 235 completed results in 161 families. Only 10 analyses (4.3%) proved uninformative, but a further 5 requests (1.9%) could not...

Topics

Adolescent
Adult
Chromosomes, Human, Pair 19
DNA
Female
Genetic Linkage
Genetic Markers
Genotype
Humans
Male
Middle Aged
Myotonic Dystrophy
Pedigree
Phenotype
Pregnancy
Prenatal Diagnosis

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