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Article

A genetic study of the role of the Wnt/beta-catenin signalling in Paneth cell differentiation.

Developmental biology - 15 Dec 2008

Andreu Pauline, Peignon Grégory, Slomianny Christian, Taketo Makoto M, Colnot Sabine, Robine Sylvie, Lamarque Dominique, Laurent-Puig Pierre, Perret Christine, Romagnolo Béatrice

Abstract excerpt

Wnt/beta-catenin signalling plays a key role in the homeostasis of the intestinal epithelium. Whereas its role in the maintenance of the stem cell compartment has been clearly demonstrated, its role in the Paneth cell fate remains unclear. We performed genetic studies to elucidate the functions of the Wnt/beta-catenin pathway in Paneth cell differentiation. We analysed mice with inducible gain-of-function...

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Identifiers

PMID: 18948094
DOI: 10.1016/j.ydbio.2008.09.027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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