Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Generation of a prostate from a single adult stem cell.

Nature - 11 Dec 2008

Leong Kevin G, Wang Bu-Er, Johnson Leisa, Gao Wei-Qiang

Abstract excerpt

The existence of prostate stem cells (PSCs) was first postulated from the observation that normal prostate regeneration can occur after repeated cycles of androgen deprivation and replacement in rodents. Given the critical role of PSCs in maintaining prostate tissue integrity and their potential involvement in prostate tumorigenesis, it is important to define specific markers for normal PSCs. Several cell-surface...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adult Stem Cells
Share to Antigens, Surface
Share to Epithelium

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation

Share to Mice, Inbred C57BL

Share to Prostate

Share to Proto-Oncogene Proteins c-kit

Share to Stem Cell Transplantation

Source

Identifiers

PMID: 18946470
DOI: 10.1038/nature07427

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Generation of a prostate from a single adult stem cell.PMID 18946470Read ↗

Stem cells: The root of prostate cancer?Semantic proximity Read ↗

Therapeutic implications of cancer stem cells in prostate cancerSemantic proximity Read ↗

Prospective Identification of Tumorigenic Prostate Cancer Stem CellsSemantic proximity Read ↗

Prostate cancer stem/progenitor cells: Identification, characterization, and implicationsSemantic proximity Read ↗

A tumour stem cell hypothesis for the origins of prostate cancer.Semantic proximity Read ↗

Stem cells in prostate cancer: treating the root of the problemSemantic proximity Read ↗

The Molecular Biology of Prostate Cancer Stem Cells: From the Past to the FutureSemantic proximity Read ↗

Concise Review: Prostate Cancer Stem Cells: Current UnderstandingSemantic proximity Read ↗

Mesenchymal stem cells and prostate cancer: A concise review of therapeutic potentials and biological aspectsSemantic proximity Read ↗

Prostate cancer stem cells: a new target for therapy.Semantic proximity Read ↗

Identification of a stem cell candidate in the normal human prostate glandSemantic proximity Read ↗

Tumour-initiating stem-like cells in human prostate cancer exhibit increased NF-κB signallingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.