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Article

Hydrogen peroxide induced repression of <i>icaADBC</i> transcription and biofilm development in <i>Staphylococcus epidermidis</i>

22 Oct 2008

Abstract excerpt

Expression of the icaADBC-encoded polysaccharide intercellular adhesion by Staphylococcus epidermidis promotes biofilm formation and represents an important virulence factor in biomaterial-related infections following orthopedic surgery. Biofilm development by the pathogen can be viewed as a protective reaction to environmental stressors including osmotic stress, thermal stress, and antimicrobial chemotherapy....

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PMID: 18942741
DOI: 10.1002/jor.20758

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