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Article

Evidence for <i>icaADBC</i> -Independent Biofilm Development Mechanism in Methicillin-Resistant <i>Staphylococcus aureus</i> Clinical Isolates

1 Apr 2005

Abstract excerpt

Synthesis of a polysaccharide adhesin by icaADBC-encoded enzymes is currently the best-understood mechanism of staphylococcal biofilm development. In four methicillin-resistant Staphylococcus aureus isolates, environmental activation of icaADBC did not always correlate with increased biofilm production. Moreover, glucose-mediated biofilm development in these isolates was icaADBC independent. Apparently, an...

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PMID: 15815035
DOI: 10.1128/jcm.43.4.1973-1976.2005

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