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Article

Mutation and copy number analysis of LNX1 and Numbl in nervous system tumors.

Cancer genetics and cytogenetics - 15 Oct 2008

Blom Tea, Roselli Annariikka, Tanner Minna, Nupponen Nina N

Abstract excerpt

Alterations at chromosome locus 4q12 are frequently found in gliomas; this locus contains the receptor tyrosine kinase--encoding genes KIT, PDGFRA, and KDR (alias VEGFR2). Notable among the genes at this locus is LNX1, the ligand of Numb protein X. LNX1 encodes a PDZ domain containing protein, which interacts with the cell fate determinant Numbl, a Numb homolog-like gene involved in the maintenance of neural...

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Source

Identifiers

PMID: 18940473
DOI: 10.1016/j.cancergencyto.2008.07.003

Genes

LNX1
KIT
KDR
PDGFRA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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