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Article

Nucleic acid from saliva and salivary cells for noninvasive genotyping of Crohn's disease patients.

Genetic testing - 1 Dec 2008

Hong Jiwon, Leung Euphemia, Fraser Alan, Krissansen Geoffrey Wayne

Abstract excerpt

CARD15 genes carrying the 3020insC frameshift polymorphism encode a truncated CARD15 protein that is unresponsive to bacterial muramyl dipeptide, and are strongly associated with increased susceptibility to Crohn's disease (CD). In this study we established that CARD15 gene sequences encompassing the major 3020insC polymorphism could be readily amplified from the DNA found in saliva. In addition, CARD15 RNA...

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Identifiers

PMID: 18939941
DOI: 10.1089/gte.2008.0027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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