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Article

Use of dried blood spot specimens in the detection of human immunodeficiency virus type 1 by the polymerase chain reaction

1 Apr 1991

Abstract excerpt

Dried blood spots (DBSs) constitute a potentially valuable source of material for human immunodeficiency virus (HIV) serologic and molecular testing. To facilitate molecular testing, we have adapted the polymerase chain reaction (PCR) to the detection of HIV proviral DNA in DBS samples. The method is highly reproducible, with 75 microliters of whole dried blood providing sufficient DNA for duplicate testing with...

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PMID: 1890166
DOI: 10.1128/jcm.29.4.667-671.1991

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