Article
Evaluation of dried blood spots for human immunodeficiency virus type 1 drug resistance testing.
Journal of clinical microbiology - 1 Feb 2007
McNulty Amanda, Jennings Cheryl, Bennett Diane, Fitzgibbon Joseph, Bremer James W, Ussery Michael, Kalish Marcia L, Heneine Walid, García-Lerma J Gerardo
Abstract excerpt
Dried blood spots (DBS) are simpler to prepare, store, and transport than plasma or serum and may represent a good alternative for drug resistance genotyping, particularly in resource-limited settings. However, the utility of DBS for drug resistance testing is unknown. We investigated the efficiency of amplification of large human immunodeficiency virus type 1 (HIV-1) pol fragments (1,023 bp) from DBS stored at...
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