Article
Evaluating the role of etravirine in the second-line antiretroviral therapy after failing an initial non-nucleoside reverse transcriptase inhibitor-based regimen in a resource-limited setting.
Current HIV research - 1 Sept 2008
Sungkanuparph Somnuek, Manosuthi Weerawat, Kiertiburanakul Sasisopin, Piyavong Bucha, Chantratita Wasun
Abstract excerpt
Etravirine demonstrates activity against NNRTI-resistant HIV-1 but its efficacy depends on the number of etravirine resistance-associated mutations (RAMs). This study aimed to evaluate the role of etravirine in the second regimen in a resource-limited setting. Genotype resistance assay was conducted in a cohort of HIV-infected patients who experienced virological failure from an initial NNRTI-based regimen. We...
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