Article
JAK2 V617F mutation testing in polycythemia vera: use and impact in an academic practice.
The American journal of the medical sciences - 1 Oct 2008
Means Robert T
Abstract excerpt
BACKGROUND: The observation that a mutation in JAK2 (JAK2 V617F) is present in more than 90% of cases of polycythemia vera (PV) has altered the diagnostic approach to this disease. However, most studies of the utility of JAK2 V617F have been performed in large PV populations; most hematologists or hematologist-oncologists have relatively few PV patients in their individual practices. APPROACH: To assess its...
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