Article
Usefulness of JAK2V617F mutation in distinguishing idiopathic erythrocytosis from polycythemia vera.
Leukemia research - 1 Jan 2007
Rossi Davide, Cortini Francesca, Deambrogi Clara, Barbieri Caterina, Cerri Michaela, Franceschetti Silvia, Conconi Annarita, Capello Daniela, Gaidano Gianluca
Abstract excerpt
Idiopathic erythrocytosis (IE) is a primary erythrocytosis not fulfilling the criteria for polycythemia vera (PV) diagnosis. In order to verify the relationship between IE and PV, we screened JAK2V617F mutation in a consecutive series of 11 IE and, for comparison, in 15 PV. JAK2V617F mutation was screened by both cDNA sequencing and mutation specific PCR in both peripheral blood and bone marrow samples. All 11 IE...
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