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Article

Azole resistance in Mycobacterium tuberculosis is mediated by the MmpS5-MmpL5 efflux system.

Tuberculosis (Edinburgh, Scotland) - 1 Jan 2009

Milano Anna, Pasca Maria Rosalia, Provvedi Roberta, Lucarelli Anna Paola, Manina Giulia, Ribeiro Ana Luisa de Jesus Lopes, Manganelli Riccardo, Riccardi Giovanna

Abstract excerpt

Tuberculosis (TB) remains the leading cause of mortality due to a bacterial pathogen, Mycobacterium tuberculosis. Moreover, the recent isolation of M. tuberculosis strains resistant to both first- and second-line antitubercular drugs (XDR-TB) threatens to make the treatment of this disease extremely difficult and becoming a threat to public health worldwide. Recently, it has been shown that azoles are potent...

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Identifiers

PMID: 18851927
DOI: 10.1016/j.tube.2008.08.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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