Article
Bacterial overgrowth and inflammation of small intestine after carboxymethylcellulose ingestion in genetically susceptible mice.
Inflammatory bowel diseases - 1 Mar 2009
Swidsinski Alexander, Ung Victoria, Sydora Beate C, Loening-Baucke Vera, Doerffel Yvonne, Verstraelen Hans, Fedorak Richard N
Abstract excerpt
BACKGROUND: Detergents and emulsifiers added to food may destroy the mucus barrier, which normally isolates bacteria from the intestinal wall, and lead to chronic bowel inflammation in susceptible persons. We investigated the influence of 2% carboxymethylcellulose (CMC) on the biostructure of the intestinal microbiota in IL-10 gene-deficient mice. METHODS: Twenty to 27-week-old IL-10 gene-deficient mice received...
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