Article
TMFunction: database for functional residues in membrane proteins.
Nucleic acids research - 1 Jan 2009
Gromiha M Michael, Yabuki Yukimitsu, Suresh M Xavier, Thangakani A Mary, Suwa Makiko, Fukui Kazuhiko
Abstract excerpt
We have developed the database TMFunction, which is a collection of more than 2900 experimentally observed functional residues in membrane proteins. Each entry includes the numerical values for the parameters IC50 (measure of the effectiveness of a compound in inhibiting biological function), V(max) (maximal velocity of transport), relative activity of mutants with respect to wild-type protein, binding affinity,...
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