Article
Variations in the transcriptome of Alzheimer's disease reveal molecular networks involved in cardiovascular diseases.
Genome biology - 8 Oct 2008
Ray Monika, Ruan Jianhua, Zhang Weixiong
Abstract excerpt
BACKGROUND: Because of its polygenic nature, Alzheimer's disease is believed to be caused not by defects in single genes, but rather by variations in a large number of genes and their complex interactions. A systems biology approach, such as the generation of a network of co-expressed genes and the identification of functional modules and cis-regulatory elements, to extract insights and knowledge from microarray...
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