Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Global transcriptional response to mammalian temperature provides new insight into Francisella tularensis pathogenesis.

BMC microbiology - 8 Oct 2008

Horzempa Joseph, Carlson Paul E, O'Dee Dawn M, Shanks Robert M Q, Nau Gerard J

Abstract excerpt

BACKGROUND: After infecting a mammalian host, the facultative intracellular bacterium, Francisella tularensis, encounters an elevated environmental temperature. We hypothesized that this temperature change may regulate genes essential for infection. RESULTS: Microarray analysis of F. tularensis LVS shifted from 26 degrees C (environmental) to 37 degrees C (mammalian) showed approximately 11% of this bacterium's...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Temperature
Share to Chick Embryo

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Dendritic Cells

Share to Francisella tularensis

Share to Gene Expression Regulation, Bacterial

Share to Macrophages

Share to RNA, Bacterial

Share to Tularemia

Source

Open in PubMed Open full text

Identifiers

PMID: 18842136
DOI: 10.1186/1471-2180-8-172
PMCID: PMC2576331

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Global transcriptional response to mammalian temperature provides new insight into Francisella tularensis pathogenesis.PMID 18842136Read ↗

Intracellular biology and virulence determinants of<i>Francisella tularensis</i>revealed by transcriptional profiling inside macrophagesSemantic proximity Read ↗

Identification of MglA-regulated genes reveals novel virulence factors in Francisella tularensis.Semantic proximity Read ↗

Cell biology and molecular ecology of<i>Francisella tularensis</i>Semantic proximity Read ↗

The Francisella pathogenicity island protein PdpD is required for full virulence and associates with homologues of the type VI secretion system.Semantic proximity Read ↗

Uncovering the components of the Francisella tularensis virulence stealth strategy.Semantic proximity Read ↗

Identification of a Novel Francisella tularensis Factor Required for Intramacrophage Survival and Subversion of Innate Immune ResponseSemantic proximity Read ↗

An intracellularly inducible gene involved in virulence and polyphosphate production in Francisella.Semantic proximity Read ↗

Whole-Genome Relationships among Francisella Bacteria of Diverse Origins Define New Species and Provide Specific Regions for Detection.Semantic proximity Read ↗

Generation and characterization of an attenuated mutant in a response regulator gene of Francisella tularensis live vaccine strain (LVS).Semantic proximity Read ↗

<i>Francisella tularensis</i>regulates autophagy-related host cell signaling pathwaysSemantic proximity Read ↗

Structure of the Potential Virulence Factor from Francisella tularensis Shows Unexpected Presence of the SHS2 Motif and Similarity to Other Bacterial Virulence FactorsSemantic proximity Read ↗

Comparative phosphoproteomics reveals components of host cell invasion and post-transcriptional regulation during Francisella infection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.