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Quantitative Plasma Hypermethylated DNA Markers of Undifferentiated Nasopharyngeal Carcinoma

1 Apr 2004

Abstract excerpt

PURPOSE: Gene-specific methylation is common in primary undifferentiated nasopharyngeal carcinoma (NPC). DNA released from apoptotic or necrotic cell death including those aberrantly methylated promoter DNA of cancer cells is absorbed into the circulation as cell-free plasma DNA of the patient. This study aims at evaluation of the potential use of methylated gene promoter DNA as a serological tumor marker of...

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Share to Epigenetics and DNA Methylation
Share to Genomic variations and chromosomal abnormalities
Share to Head and Neck Cancer Studies

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Identifiers

PMID: 15073117
DOI: 10.1158/1078-0432.ccr-03-0139

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Source receipt: pubmed, retrieved 7 Sept 2026.

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