Article
Chemical individuality: concept and outlook.
Journal of inherited metabolic disease - 1 Oct 2008
Gahl W A
Abstract excerpt
Sir Archibald Garrod's concept of chemical individuality introduced a century ago provided the basis for the entire discipline of inborn errors of metabolism. Human disorders are defined by variation in disease-causing mutations, environmental influences, genetic factors other than the primary genetic defect, and evolution itself. Myriad examples support the prescience of Garrod with respect to these issues, each...
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