Article
Haplotype sorting using human fosmid clone end-sequence pairs.
Genome research - 1 Dec 2008
Kidd Jeffrey M, Cheng Ze, Graves Tina, Fulton Bob, Wilson Richard K, Eichler Evan E
Abstract excerpt
An important goal of human genetics and genomics is to understand the complete spectrum of genetic variation across a specific human haplotype. By combining information from a dense SNP map with fosmid end-sequence pairs (ESPs) aligned to the human genome reference sequence, we have developed a simple method to resolve human haplotypes using a previously developed clone resource. By partitioning ESPs into either...
Topics
- Base Pairing
- Base Sequence
- Black People
- Chromosome Mapping
- Cloning, Molecular
- Genetics, Population
- Genome, Human
- Genotype
- Haplotypes
- Homozygote
- Humans
- Molecular Sequence Data