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Article

Comprehensive mutational analysis of yeast DEXD/H box RNA helicases involved in large ribosomal subunit biogenesis.

Molecular and cellular biology - 1 Feb 2006

Bernstein Kara A, Granneman Sander, Lee Alicia V, Manickam Swarnameenakshi, Baserga Susan J

Abstract excerpt

DEXD/H box putative RNA helicases are required for pre-rRNA processing in Saccharomyces cerevisiae, although their exact roles and substrates are unknown. To characterize the significance of the conserved motifs for helicase function, a series of five mutations were created in each of the eight essential RNA helicases (Has1, Dbp6, Dbp10, Mak5, Mtr4, Drs1, Spb4, and Dbp9) involved in 60S ribosomal subunit...

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Identifiers

PMID: 16449635
DOI: 10.1128/MCB.26.4.1195-1208.2006
PMCID: PMC1367183

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Comprehensive mutational analysis of yeast DEXD/H box RNA helicases involved in large ribosomal subunit biogenesis.PMID 16449635Read ↗

Comprehensive mutational analysis of yeast DEXD/H box RNA helicases required for small ribosomal subunit synthesis.Semantic proximity Read ↗

Characterization and mutational analysis of yeast Dbp8p, a putative RNA helicase involved in ribosome biogenesis.Semantic proximity Read ↗

Dbp7p, a putative ATP-dependent RNA helicase from Saccharomyces cerevisiae, is required for 60S ribosomal subunit assembly.Semantic proximity Read ↗

Dbp10p, a putative RNA helicase from Saccharomyces cerevisiae, is required for ribosome biogenesis.Semantic proximity Read ↗

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DRS1 to DRS7, novel genes required for ribosome assembly and function in Saccharomyces cerevisiae.Semantic proximity Read ↗

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The DEAD box protein Mrh4 functions in the assembly of the mitochondrial large ribosomal subunit.Semantic proximity Read ↗

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