Article
Comprehensive mutational analysis of yeast DEXD/H box RNA helicases involved in large ribosomal subunit biogenesis.
Molecular and cellular biology - 1 Feb 2006
Bernstein Kara A, Granneman Sander, Lee Alicia V, Manickam Swarnameenakshi, Baserga Susan J
Abstract excerpt
DEXD/H box putative RNA helicases are required for pre-rRNA processing in Saccharomyces cerevisiae, although their exact roles and substrates are unknown. To characterize the significance of the conserved motifs for helicase function, a series of five mutations were created in each of the eight e...
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