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Article

Histidine-regulated activity of M-ficolin.

The Biochemical journal - 15 Jan 2009

Tanio Michikazu, Kohno Toshiyuki

Abstract excerpt

Human M-ficolin is a pathogen-associated molecular recognition molecule in the innate immune system, and it binds to some sugars, such as GlcNAc (N-acetylglucosamine), on pathogen surfaces. From previous structural and functional studies of the FD1 (M-ficolin fibrinogen-like domain), we proposed that the ligand-binding region of FD1 exists in a conformational equilibrium between active and non-active states...

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Source

Identifiers

PMID: 18826375
DOI: 10.1042/BJ20081640

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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