Article
Genetic variations of the chemokine scavenger receptor D6 are associated with liver inflammation in chronic hepatitis C.
Human immunology - 1 Dec 2008
Wiederholt Tonio, von Westernhagen Michael, Zaldivar Mirko Moreno, Berres Marie-Luise, Schmitz Petra, Hellerbrand Claus, Müller Tobias, Berg Thomas, Trautwein Christian, Wasmuth Hermann E
Abstract excerpt
Chronic hepatitis C (HCV) represents one of the most common chronic infections worldwide and is a major indication for liver transplantation. Liver inflammation is the main predictor of advanced fibrosis in HCV. Inflammatory cells are recruited to the liver by chemokines. Recently, a novel class of chemokine receptors has been characterized that lack signaling functions and are termed scavenger receptors. We...
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