Article
SULT1E1 and ID2 genes as candidates for inherited predisposition to breast and ovarian cancer in Jewish women.
Familial cancer - 1 Jan 2009
Cohen Shimrit, Laitman Yael, Kaufman Bella, Milgrom Roni, Nir Uri, Friedman Eitan
Abstract excerpt
Mutations in currently known genes account for only a subset of breast/ovarian cancer risk families. Three loci (2p, 4q, 22q) seemingly harbor breast cancer susceptibility genes. To explore their putative role in Jewish women, 46 affected women representing 22 high risk families were genotyped with D2S2211, D4S392, D22S278 and D22S283 and two flanking markers for each locus, and mutational analysis of ID2...
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