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Article

A common RET variant is associated with reduced newborn kidney size and function.

Journal of the American Society of Nephrology : JASN - 1 Oct 2008

Zhang Zhao, Quinlan Jackie, Hoy Wendy, Hughson Michael D, Lemire Mathieu, Hudson Thomas, Hueber Pierre-Alain, Benjamin Alice, Roy Anne, Pascuet Elena, Goodyer Meigan, Raju Chandhana, Houghton Fiona, Bertram John, Goodyer Paul

Abstract excerpt

Congenital nephron number varies five-fold among normal humans, and individuals at the lower end of this range may have an increased lifetime risk for essential hypertension or renal insufficiency; however, the mechanisms that determine nephron number are unknown. This study tested the hypothesis...

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Source

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Identifiers

PMID: 18820179
DOI: 10.1681/ASN.2007101098
PMCID: PMC2551577

Genes

RET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18820179-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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